Planting Flowers and Assembling Complex Systems

Assembling large, complex environmental metagenomes

The large volumes of sequencing data required to sample complex environments deeply pose new challenges to sequence analysis approaches. De novo metagenomic assembly effectively reduces the total amount of data to be analyzed but requires significant computational resources. We apply two pre-assembly filtering approaches, digital normalization and partitioning , to make large metagenome assembl...

Complex fuzzy linear systems

Self-assembling peptide systems

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String Assembling Systems

We introduce and investigate string assembling systems which form a computational model that generates strings from copies out of a finite set of assembly units. The underlying mechanism is based on piecewise assembly of a double-stranded sequence of symbols, where the upper and lower strand have to match. The generation is additionally controlled by the requirement that the first symbol of a u...

Self-Assembling Systems are Distributed Systems

In 2004, Klavins et al. introduced the use of graph grammars to describe—and to program— systems of self-assembly. We show that these graph grammars can be embedded in a graph rewriting characterization of distributed systems that was proposed by Degano and Montanari over twenty years ago. We apply this embedding to generalize Soloveichik and Winfree’s local determinism criterion (for achieving...